Young Ji Na, PH.D

Education

• B.A. Biology and Computer Science
  Handong University
• Ph.D. Bioinformatics
  Seoul National University

TECHNOLOGY AREAS

• Bioinformatics
• Data Science
• Machine Learning

PRIOR PROFESSIONAL EXPERIENCE

• Senior Scientist, Genomic Medicine Unit, Sanofi, 2020-2024
• Adjunct Instructor, Department of Medicine, Columbia University, 2020-2022
• Instructor, Department of Medicine, Columbia University, 2019-2020
• Postdoctoral Research Scientist, Department of Medicine, Columbia University, 2016-2019
• Postdoctoral Fellow, Department of Biology, University of Pennsylvania, 2013-2016
• Research Assistant Professor, Hospital for Rheumatic Diseases, Hanyang University, 2013

AWARDS AND RECOGNITION

• NIH, Mentored Research Scientist Development Award (K01), 1K01DK119540-91
• Columbia University, Dr. Ines Mandl Connective Tissue Research Fellowship
• Brain Korea Best Student Award

LANGUAGE CAPABILITIES

• English
• Korean

PROFESSIONAL MEMBERSHIPS & ACTIVITIES

• Registered to Practice before the United States Patent and Trademark Office (USPTO)

SELECTED PUBLICATIONS

• “Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection,” N Engl J Med. 2019 May 16;380(20):1918-1928.
• “The copy number variation landscape of congenital anomalies of the kidney and urinary tract,” Nat Genet. 2019 Jan;51(1):117-127.
• “Diagnosis of traumatic brain injury using miRNA signatures in nanomagnetically isolated brain-derived extracellular vesicles,” Lab Chip. 2018 Dec 7;18(23):3617-3630.
• “miRNA Profiling of Magnetic Nanopore-Isolated Extracellular Vesicles for the Diagnosis of Pancreatic Cancer,” Cancer Res. 2018 Jul 1;78(13):3688-3697.
• “Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing,” Cell Rep. 2017 Dec 5;21(10):2706-2713.
• “Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations,” Am J Hum Genet. 2017 Dec 7;101(6):1034.
• “Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics,” Cell Rep. 2017 Jan 17;18(3):791-803.
• “High-resolution transcriptome analysis reveals neuropathic pain gene-expression signatures in spinal microglia after nerve injury,” Pain. 2016 Apr;157(4):964-976.
• “Interpretation of personal genome sequencing data in terms of disease ranks based on mutual information,” BMC Med Genomics. 2015;8 Suppl 2(Suppl 2):S4.
• “Targeted exon sequencing fails to identify rare coding variants with large effect in rheumatoid arthritis,” Arthritis Res Ther. 2014 Sep 30;16(5):447.
• “Ethnic specificity of lupus-associated loci identified in a genome-wide association study in Korean women,” Ann Rheum Dis. 2014 Jun;73(6):1240-5.
• “Understanding cooperativity of microRNAs via microRNA association networks,” BMC Genomics. 2013;14 Suppl 5(Suppl 5):S17.
• “AnsNGS: An Annotation System to Sequence Variations of Next Generation Sequencing Data for Disease-Related Phenotypes,” Healthc Inform Res. 2013 Mar;19(1):50-5.
• “Comprehensive analysis of microRNA-mRNA co-expression in circadian rhythm,” Exp Mol Med. 2009 Sep 30;41(9):638-47.
• “Comprehensive analysis of time- and dose-dependent patterns of gene expression in a human mesenchymal stem cell line exposed to low-dose ionizing radiation,” Oncol Rep. 2008 Jan;19(1):135-44.
• Inventor of U.S. Patent Application No. PCT/US2024/012590:
  “Predicting INDEL Frequencies”
• Inventor of U.S. Patent Application No. PCT/US2023/082543:
  “Detecting Viral Sequences in Metagenome Data”